Presupuesto público en salud y sus efectos en la desnutrición crónica infantil. El caso peruano / Public health budget and its effects on chronic child malnutrition. The Peruvian case / Orçamento da saúde pública e seus efeitos sobre a desnutrição infantil crônica. O caso peruano

En la actualidad, aunque las tasas de malnutrición que afectan a los pueblos indígenas y a las zonas de bajos ingresos han disminuido en un 33,8%, América Latina sigue registrando niveles alarmantes de malnutrición, especialmente a nivel infantil. En el caso de Perú en particular, urge estudiar el impacto del presupuesto sanitario en la dinámica de la desnutrición infantil. Objetivo. Analizar la incidencia del presupuesto de salud pública en la reducción de la desnutrición infantil en Perú durante las dos últimas décadas. Metodología. Revisión narrativa acerca del impacto de los presupuestos de salud pública en la desnutrición. Dentro de busqueda se consideraron bases de datos como Scopus, Web of Science, Scielo, Redalyc, Latindex y Google Scholar desde el 2019 a 2023. Considerando con ecuación health budget" OR "chronic child malnutrition", "government spending" con la función booleana AND como parámetros de búsqueda para el campo "topic" para encontrar documentos que también trataran sobre "malnutrition" OR "chronic child malnutrition" OR "child malnutrition". Resultados. Se identificaron 57 fuente, se excluyeron 4 artículos por duplicidad y 37 por falta de información, dando como resultando un total de 16 artículos a considerar en este análisis. Conclusión. Se puede concluir que existe una relación significativa entre el aumento del presupuesto público en salud y la disminución de la desnutrición infantil a nivel nacional. La literatura existente destaca que a medida que se incrementa la asignación presupuestaria en el ámbito de la salud, se observa una reducción correspondiente en las tasas de desnutrición.

Currently, although malnutrition rates affecting indigenous peoples and low-income areas have decreased by 33.8%, Latin America continues to register alarming levels of malnutrition, especially at the child level. In the case of Peru in particular, there is an urgent need to study the impact of the health budget on the dynamics of child malnutrition. Objective. To analyze the impact of the public health budget on the reduction of child malnutrition in Peru during the last two decades. Methodology. Narrative review of the impact of public health budgets on malnutrition. Within the search, databases such as Scopus, Web of Science, Scielo, Redalyc, Latindex and Google Scholar from 2019 to 2023 were considered. Considering with equation health budget" OR "chronic child malnutrition", "government spending" with the Boolean function AND as search parameters for the field "topic" to find documents that also dealt with "malnutrition" OR "chronic child malnutrition" OR "child malnutrition". Results. Fifty-seven sources were identified, 4 articles were excluded due to duplicity and 37 due to lack of information, resulting in a total of 16 articles to be considered in this analysis. Conclusion. It can be concluded that there is a significant relationship between the increase in the public health budget and the decrease in child malnutrition at the national level. The existing literature highlights that as the health budget allocation increases, a corresponding reduction in malnutrition rates is observed.

Atualmente, embora as taxas de desnutrição que afetam os povos indígenas e as áreas de baixa renda tenham diminuído em 33,8%, a América Latina continua a registrar níveis alarmantes de desnutrição, especialmente no nível infantil. No caso do Peru, em particular, há uma necessidade urgente de estudar o impacto do orçamento da saúde na dinâmica da desnutrição infantil. Objetivo. Analisar o impacto do orçamento da saúde pública na redução da desnutrição infantil no Peru nas últimas duas décadas. Metodologia. Revisão narrativa do impacto dos orçamentos públicos de saúde sobre a desnutrição. Bases de dados como Scopus, Web of Science, Scielo, Redalyc, Latindex e Google Scholar de 2019 a 2023 foram consideradas na pesquisa. Considerando com equação "health budget" OR "chronic child malnutrition", "government spending" com a função booleana AND como parâmetros de pesquisa para o campo "topic" para encontrar documentos que também tratassem de "malnutrition" OR "chronic child malnutrition" OR "child malnutrition". Resultados. Foram identificadas 57 fontes, 4 artigos foram excluídos devido à duplicação e 37 devido à falta de informações, resultando em um total de 16 artigos a serem considerados nesta análise. Conclusão. Pode-se concluir que existe uma relação significativa entre o aumento do orçamento da saúde pública e a redução da desnutrição infantil em nível nacional. A literatura existente destaca que, à medida que a alocação do orçamento de saúde aumenta, observa-se uma redução correspondente nas taxas de desnutrição.

Proteomic analysis of the hepatic response to a pollutant mixture in mice. The protective action of selenium.

Metals and pharmaceuticals contaminate water and food worldwide, forming mixtures where they can interact to enhance their individual toxicity. Here we use a shotgun proteomic approach to evaluate the toxicity of a pollutant mixture (PM) of metals (As, Cd, Hg) and pharmaceuticals (diclofenac, flumequine) on mice liver proteostasis. These pollutants are abundant in the environment, accumulate in the food chain, and are toxic to humans primarily through oxidative damage. Thus, we also evaluated the putative antagonistic effect of low-dose dietary supplementation with the antioxidant trace element selenium. A total of 275 proteins were affected by PM treatment. Functional analyses revealed an increased abundance of proteins involved in the integrated stress response that promotes translation, the inflammatory response, carbohydrate and lipid metabolism, and the sustained expression of the antioxidative response mediated by NRF2. As a consequence, a reductive stress situation arises in the cell that inhibits the RICTOR pathway, thus activating the early stage of autophagy, impairing xenobiotic metabolism, and potentiating lipid biosynthesis and steatosis. PM exposure-induced hepato-proteostatic alterations were significantly reduced in Se supplemented mice, suggesting that the use of this trace element as a dietary supplement may at least partially ameliorate liver damage caused by exposure to environmental mixtures.

A selenium-enriched diet helps to recover liver function after antibiotic administration in mice.

Antibiotic (Abx) treatments or inadvertent exposure to Abx-contaminated food and water can adversely affect health. Many studies show strong correlations between Abx and liver damage pointing to gut dysbiosis as a contributing factor because the gut microbiota (GM) forms a complex network with liver. Selenium (Se) is a beneficial micronutrient able to shape the composition of the GM. We analyzed here the ability of a low dose (120 µg/kg bodyweight/day) Se-enriched diet to ameliorate the effects of a 7-day intervention with an Abx-cocktail over the global health and the homeostasis of cholesterol and bile acids in the mouse liver. We found that Se restored lipid metabolism preventing the increased synthesis and accumulation of cholesterol caused by Abx treatment. Integrating these results with previous metataxonomic and metabolomic data in same mice, we conclude that part of the effect of Se against liver dysfunction (cholesterol and bile acids metabolism and transport) could be mediated by the GM. We provide data that contribute to a more complete view of the molecular mechanisms underlying the beneficial action of Se on health, pointing to a possible use of low doses of Se as a functional food additive (prebiotic) to prevent the negative effects of antibiotics.

Modeling of the 3D Tree Skeleton Using Real-World Data: A Survey.

Tree modeling has been extensively studied in computer graphics. Recent advances in the development of high-resolution sensors and data processing techniques are extremely useful for collecting 3D datasets of real-world trees and generating increasingly plausible branching structures. The wide availability of versatile acquisition platforms allows us to capture multi-view images and scanned data that can be used for guided 3D tree modeling. In this paper, we carry out a comprehensive review of the state-of-the-art methods for the 3D modeling of botanical tree geometry by taking input data from real scenarios. A wide range of studies has been proposed following different approaches. The most relevant contributions are summarized and classified into three categories: (1) procedural reconstruction, (2) geometry-based extraction, and (3) image-based modeling. In addition, we describe other approaches focused on the reconstruction process by adding additional features to achieve a realistic appearance of the tree models. Thus, we provide an overview of the most effective procedures to assist researchers in the photorealistic modeling of trees in geometry and appearance. The article concludes with remarks and trends for promising research opportunities in 3D tree modeling using real-world data.

Diferencias entre ginecólogos y residentes en habilidades motoras básicas de un módulo de ejercicios de un sistema virtual de simulación / Differences between gynecologists and medical residents in basic motor skills of an exercise module of a virtual simulation system

Resumen OBJETIVO: Evaluar las diferencias en los desenlaces de los ejercicios del módulo de habilidades motoras básicas del simulador Simbionix LAP Mentor entre un grupo de residentes de Ginecología y otro de especialistas en cirugía laparoscópica. MATERIALES Y MÉTODOS: Estudio observacional, prospectivo, longitudinal y comparativo efectuado de diciembre de 2019 a enero de 2020 en el Hospital Español de México. Se seleccionaron médicos residentes de Ginecología y especialistas en la misma rama con experiencia diversa en cirugía laparoscópica. Se evaluaron, con un programa de adiestramiento mediante simulación de alta fidelidad, los ejercicios del módulo de habilidades motoras básicas de un sistema de realidad virtual. Para las variables con distribución normal se aplicó la prueba de t de Student y la de U de Mann-Whitney para las variables que no cumplieron el criterio de normalidad. RESULTADOS: Se incluyeron 31 participantes: el grupo de especialistas (n = 19) y el de residentes (n = 12). Se encontraron diferencias significativas entre residentes y especialistas en el ejercicio 3-coordinación ojo-mano (4.45 seg, IC95%: 0.167-8.73; p < 0.05) y en el ejercicio 5-tracción y engrapado de mangueras con fugas (29.58 seg, IC95%: -42.99 -14.00; p < 0.001), a favor del grupo de especialistas. En los ejercicios 7-corte y ejercicio 8-fulguración no hubo diferencias significativas entre uno y otro grupo. CONCLUSIONES: El simulador de realidad virtual Simbionix LAP Mentor detecta diferencias entre grupos de ginecoobstetras con diferente experiencia en cirugía ginecológica de mínima invasión y residentes de la especialidad.

Abstract OBJECTIVE: To evaluate the differences in the outcomes of the exercises of the basic motor skills module of the Simbionix LAP Mentor simulator between a group of gynecology residents and another group of already graduated specialists. MATERIALS AND METHODS: Observational, prospective, longitudinal and comparative study carried out from December 2019 to January 2020 at the Hospital Español de México. Gynecology residents and specialists in the same branch with diverse experience in laparoscopic surgery were selected. The exercises of the basic motor skills module of a virtual reality system were evaluated with a high-fidelity simulation training program. The Student's t test was applied for variables with normal distribution and the Mann-Whitney U test for variables that did not meet the normality criterion. RESULTS: Thirty-one participants were included: the specialist group (n = 19) and the resident group (n = 12). Significant differences between residents and specialists were found in exercise 3-eye-hand coordination (4.45 sec, 95%CI: 0.167-8.73; p < 0.05) and in exercise 5-pulling and stapling of leaking hoses (29.58 sec, 95%CI: -42.99 -14.00; p < 0.001), in favor of the specialist group. In exercise 7-cutting and exercise 8-fulguration there were no significant differences between one group and the other. CONCLUSIONS: The Simbionix LAP Mentor virtual reality simulator detects differences between groups of obstetrician-gynecologists with different experience in minimally invasive gynecologic surgery and residents of the specialty.

[Body composition and physical activity in resident physicians]. / Composición corporal y actividad física en médicos residentes.

BACKGROUND: Mexico is ranked second in obesity in adults worldwide and resident physicians are not exempt from this problem. Inadequate diet and physical inactivity are associated factors. Bioimpedance has greater precision than anthropometry. OBJECTIVE: To analyze the difference between degree of physical activity, caloric intake and body composition in Internal Medicine residents according to their degree of residence. MATERIAL AND METHODS: Cross-sectional study. Resident physicians of both sexes, from second, third and fourth degree of training were included; they were fasting. Vital signs were taken; a Rapid Assessment of Physical Activity (RAPA) questionnaire, anthropometry, a 24-hour reminder, and bioelectrical impedance analysis were administered. Descriptive statistics, Kruskal-Wallis and chi squared tests were used. RESULTS: 84 resident physicians were included, 48 were male. The median age was of 27 years (26-28). There was a prevalence of 46.4% of overweight and obesity, despite the hypocaloric diet in 89%. Bioelectrical impedance analysis showed that 72.6% of residents had elevated body fat, 71% sub-optimal degree of physical activity and 23.7% arterial hypertension. CONCLUSIONS: A high prevalence of overweight and obesity was found with differences in body composition and suboptimal level of physical activity. It is important to correct bad eating habits and improve physical activity to reduce risks in this population.

INTRODUCCIÓN: México es segundo lugar mundial en obesidad en adultos y los médicos residentes no están exentos de este problema. La dieta inadecuada y la inactividad física son factores asociados. La bioimpedancia tiene mayor precisión que la antropometría. OBJETIVO: analizar la diferencia entre grado de actividad física, ingesta calórica y composición corporal en residentes de Medicina Interna de acuerdo con su grado de residencia. MATERIAL Y MÉTODOS: estudio transversal. Se incluyeron médicos residentes de ambos sexos de segundo, tercero y cuarto grado, quienes participaron en ayuno. Se les tomaron signos vitales, se les otorgó el cuestionario Rapid Assesment of Physical Activity (RAPA), antropometría, recordatorio de 24 horas y medición de composición corporal por bioimpedancia. Se empleó estadística descriptiva, prueba de Kruskal-Wallis y chi cuadrada. RESULTADOS: se incluyeron 84 médicos residentes, 48 (57.14%) fueron del género masculino. La mediana de edad fue de 27 años (26-28). Se encontró una prevalencia de sobrepeso y obesidad de 46.4% a pesar de la dieta hipocalórica en el 89%. La medición por bioimpedancia indicó que 72.6% tuvo grasa corporal elevada, 71% grado de actividad física subóptimo y 23.7% hipertensión arterial. CONCLUSIONES: se encontró una alta prevalencia de sobrepeso y obesidad con diferencias en la composición corporal y el nivel subóptimo de actividad física. Es importante corregir los malos hábitos alimenticios y mejorar la actividad física para reducir riesgos en esta población.

Composición corporal y actividad física en médicos residentes / Body composition and physical activity in resident physicians

Introducción: México es segundo lugar mundial en obesidad en adultos y los médicos residentes no están exentos de este problema. La dieta inadecuada y la inactividad física son factores asociados. La bioimpedancia tiene mayor precisión que la antropometría. Objetivo: analizar la diferencia entre grado de actividad física, ingesta calórica y composición corporal en residentes de Medicina Interna de acuerdo con su grado de residencia. Material y métodos: estudio transversal. Se incluyeron médicos residentes de ambos sexos de segundo, tercero y cuarto grado, quienes participaron en ayuno. Se les tomaron signos vitales, se les otorgó el cuestionario Rapid Assesment of Physical Activity (RAPA), antropometría, recordatorio de 24 horas y medición de composición corporal por bioimpedancia. Se empleó estadística descriptiva, prueba de Kruskal-Wallis y chi cuadrada. Resultados: se incluyeron 84 médicos residentes, 48 (57.14%) fueron del género masculino. La mediana de edad fue de 27 años (26-28). Se encontró una prevalencia de sobrepeso y obesidad de 46.4% a pesar de la dieta hipocalórica en el 89%. La medición por bioimpedancia indicó que 72.6% tuvo grasa corporal elevada, 71% grado de actividad física subóptimo y 23.7% hipertensión arterial. Conclusiones: se encontró una alta prevalencia de sobrepeso y obesidad con diferencias en la composición corporal y el nivel subóptimo de actividad física. Es importante corregir los malos hábitos alimenticios y mejorar la actividad física para reducir riesgos en esta población.

Background: Mexico is ranked second in obesity in adults worldwide and resident physicians are not exempt from this problem. Inadequate diet and physical inactivity are associated factors. Bioimpedance has greater precision than anthropometry. Objective: To analyze the difference between degree of physical activity, caloric intake and body composition in Internal Medicine residents according to their degree of residence. Material and methods: Cross-sectional study. Resident physicians of both sexes, from second, third and fourth degree of training were included; they were fasting. Vital signs were taken; a Rapid Assessment of Physical Activity (RAPA) questionnaire, anthropometry, a 24-hour reminder, and bioelectrical impedance analysis were administered. Descriptive statistics, Kruskal-Wallis and chi squared tests were used. Results: 84 resident physicians were included, 48 were male. The median age was of 27 years (26-28). There was a prevalence of 46.4% of overweight and obesity, despite the hypocaloric diet in 89%. Bioelectrical impedance analysis showed that 72.6% of residents had elevated body fat, 71% sub-optimal degree of physical activity and 23.7% arterial hypertension. Conclusions: A high prevalence of overweight and obesity was found with differences in body composition and suboptimal level of physical activity. It is important to correct bad eating habits and improve physical activity to reduce risks in this population.

GEUINF: Real-Time Visualization of Indoor Facilities Using Mixed Reality.

Mixed reality (MR) enables a novel way to visualize virtual objects on real scenarios considering physical constraints. This technology arises with other significant advances in the field of sensors fusion for human-centric 3D capturing. Recent advances for scanning the user environment, real-time visualization and 3D vision using ubiquitous systems like smartphones allow us to capture 3D data from the real world. In this paper, a disruptive application for assessing the status of indoor infrastructures is proposed. The installation and maintenance of hidden facilities such as water pipes, electrical lines and air conditioning tubes, which are usually occluded behind the wall, supposes tedious and inefficient tasks. Most of these infrastructures are digitized but they cannot be visualized onsite. In this research, we focused on the development of a new application (GEUINF) to be launched on smartphones that are capable of capturing 3D data of the real world by depth sensing. This information is relevant to determine the user position and orientation. Although previous approaches used fixed markers for this purpose, our application enables the estimation of both parameters with a centimeter accuracy without them. This novelty is possible since our method is based on a matching process between reconstructed walls of the real world and 3D planes of the replicated world in a virtual environment. Our markerless approach is based on scanning planar surfaces of the user environment and then, these are geometrically aligned with their corresponding virtual 3D entities. In a preprocessing phase, the 2D CAD geometry available from an architectural project is used to generate 3D models of an indoor building structure. In real time, these virtual elements are tracked with the real ones modeled by using ARCore library. Once the alignment between virtual and real worlds is done, the application enables the visualization, navigation and interaction with the virtual facility networks in real-time. Thus, our method may be used by private companies and public institutions responsible of the indoor facilities management and also may be integrated with other applications focused on indoor navigation.

Proteomic profile and protease activity in the skin mucus of greater amberjack (Seriola dumerili) infected with the ectoparasite Neobenedenia girellae - An immunological approach.

Skin mucus is considered the first barrier against diseases in fish. The skin mucus protein profile of the greater amberjack (Seriola dumerili) and its changes due to experimental infection with Neobenedenia girellae were studied by combining 2-DE-MS/MS and gel-free LC-MS/MS proteomic approaches. The 2-DE results led to the identification of 69 and 55 proteins in noninfected and infected fish, respectively, and revealed that keratins were specifically cleaved in parasitized fish. Therefore, the skin mucus of the infected fish showed a higher protease activity due to, at least in part, an increase of metal-dependent protease and serine-type protease activities. Additionally, through a gel-free LC-MS/MS analysis, 1377 and 1251 different proteins were identified in the skin mucus of healthy and parasitized fish, respectively. The functional analysis of these proteins demonstrated a statistical overrepresentation of ribosomal proteins (a well-known source of antimicrobial peptides) in N. girellae-infected fish. In contrast, the components of membranes and protein transport GO categories were underrepresented after infection. Immune system process-related proteins constituted 2.5% of the total skin mucosal proteins. Among these skin mucosal proteins, 14 and 15 proteins exclusive to non-parasitized and parasitized fish were found, respectively, including specific serine-type proteases and metalloproteases in the parasitized fish. Moreover, the finding of tryptic peptides exclusive to some bacterial genera, obtained by gel-free LC-MS/MS, allowed us to construct a preliminary map of the microbiota living in the mucus of S. dumerili, with Pseudomonas and Paracoccus the most represented genera in both noninfected and infected fish.

Three years prospective clinical and radiologic follow-up of laparoscopic sacrocolpoperineopexy.

BACKGROUND: When Rectocele is part of a complex pelvic organ prolapse, a full repair is recommended. The aim of this study was to evaluate the clinical and radiological results after laparoscopic surgery in patients with symptomatic rectocele and III/IV stage vaginal vault prolapse METHODS: This is a prospective cohort study of women with symptomatic rectoceles and middle compartment prolapse operated on between 2013 and 2015, who underwent a laparoscopic sacrocolpoperineopexy with synthetic Y mesh attached to puborectalis muscles, the anterior and posterior vagina wall and the sacrum. The clinical outcomes measured were symptoms of prolapse, obstructive defecation syndrome and quality of life. Radiological outcomes were distance of the vaginal vault below pubococcigeal line and depth of rectovaginal wall protrusion in dynamic pelvic resonance. RESULTS: 33 patients were included. 32 of them remained asymptomatic after a three years follow-up. Significant differences were shown in the obstructed defecation score and quality of life after 6, 12 and 36 months compared to preoperatively. No differences were identified when the postoperative results were compared. Significant differences were shown in preoperative vaginal vault prolapse (3.2 cms ± 0.8 SD below the pubococcigeal Line) and rectocele size, compared with 1 and 3 years after surgery. There were no significant differences in vaginal vault prolapse when compared after 1 and 3 years. When rectocele size after 1 and 3 years was compared, significant differences were shown, but only one clinical recurrence (3%) was identified after a mean follow-up of 47 months. CONCLUSIONS: Laparoscopic sacrocolpoperineopexy in patients with symptomatic rectocele and III/IV vaginal vault prolapse solves the constipation and obstructed defecation with an excellent quality of life and low clinical recurrences. Radiological deterioration, especially in rectocele size, was identified in the mid-term follow-up without clinical significance.

Semantic Segmentation of Natural Materials on a Point Cloud Using Spatial and Multispectral Features.

The characterization of natural spaces by the precise observation of their material properties is highly demanded in remote sensing and computer vision. The production of novel sensors enables the collection of heterogeneous data to get a comprehensive knowledge of the living and non-living entities in the ecosystem. The high resolution of consumer-grade RGB cameras is frequently used for the geometric reconstruction of many types of environments. Nevertheless, the understanding of natural spaces is still challenging. The automatic segmentation of homogeneous materials in nature is a complex task because there are many overlapping structures and an indirect illumination, so the object recognition is difficult. In this paper, we propose a method based on fusing spatial and multispectral characteristics for the unsupervised classification of natural materials in a point cloud. A high-resolution camera and a multispectral sensor are mounted on a custom camera rig in order to simultaneously capture RGB and multispectral images. Our method is tested in a controlled scenario, where different natural objects coexist. Initially, the input RGB images are processed to generate a point cloud by applying the structure-from-motion (SfM) algorithm. Then, the multispectral images are mapped on the three-dimensional model to characterize the geometry with the reflectance captured from four narrow bands (green, red, red-edge and near-infrared). The reflectance, the visible colour and the spatial component are combined to extract key differences among all existing materials. For this purpose, a hierarchical cluster analysis is applied to pool the point cloud and identify the feature pattern for every material. As a result, the tree trunk, the leaves, different species of low plants, the ground and rocks can be clearly recognized in the scene. These results demonstrate the feasibility to perform a semantic segmentation by considering multispectral and spatial features with an unknown number of clusters to be detected on the point cloud. Moreover, our solution is compared to other method based on supervised learning in order to test the improvement of the proposed approach.

Utilidad del verde de indocianina para la localización del uréter de forma intra-operatoria en cirugía colorrectal compleja / Utility of indocyanine green for intra-operative localization of ureter in complex colo-rectal surgery

No disponible

Prediction of the increase in health services demand based on the analysis of reasons of calls received by a customer relationship management.

Currently, customer relationship management (CRM) tools are very important in our society because they provide a comunication channel to the healthcare system for patients. Salud Responde is a CRM that provides many health services for the entire population of Andalusia, in southern Spain. The number and frequenzy of phone calls received change along the year. They depend on many factors, such as weekdays, seasons, vaccination campaigns, environmental factors, pandemic periods, etc. All these are the main reasons number of health calls changes along the year. This variability makes that the current management of resources for offering emergency services based on historical data is inefficient. The factors, which influence the phone calls along the year, are different from one period to another. Therefore, it is clear to demand an improved in the current management system. In this context, the main goal for this research is to develop an expert system able to identify and analyze, using different data mining algorithms, the most relevant factors to predict the variability of health service demand. Thus, here, it is proposed a methodology in which using reasons calls received in the CRM as input data, it is possible to predict in advance the healthcare resources demand.

Dietary administration of the probiotic Shewanella putrefaciens Pdp11 promotes transcriptional changes of genes involved in growth and immunity in Solea senegalensis larvae.

Senegalese sole (Solea senegalensis) has been proposed as a high-potential species for aquaculture diversification in Southern Europe. It has been demonstrated that a proper feeding regimen during the first life stages influences larval growth and survival, as well as fry and juvenile quality. The bacterial strain Shewanella putrefaciens Pdp11 (SpPdp11) has shown very good probiotic properties in Senegalese sole, but information is scarce about its effect in the earliest stages of sole development. Thus, the aim of this study was to investigate the effect of SpPdp11, bioencapsulated in live diet, administered during metamorphosis (10-21 dph) or from the first exogenous feeding of Senegalese sole (2-21 dph). To evaluate the persistence of the probiotic effect, we sampled sole specimens from metamorphosis until the end of weaning (from 23 to 73 dph). This study demonstrated that probiotic administration from the first exogenous feeding produced beneficial effects on Senegalese sole larval development, given that specimens fed this diet exhibited higher and less dispersed weight, as well as increases in both total protein concentration and alkaline phosphatase activity, and in non-specific immune response. Moreover, real-time PCR documented changes in the expression of a set of genes involved in central metabolic functions including genes related to growth, genes coding for proteases (including several digestive enzymes), and genes implicated in the response to stress and in immunity. Overall, these results support the application of SpPdp11 in the first life stages of S. senegalensis as an effective tool with the clear potential to benefit sole aquaculture.

Laparoscopic intracorporeal rectus aponeuroplasty (LIRA technique): a step forward in minimally invasive abdominal wall reconstruction for ventral hernia repair (LVHR).

BACKGROUND: Closing the defect (CD) during laparoscopic ventral hernia repair began to be performed in order to decrease seroma, to improve the functionality of the abdominal wall, and to decrease the bulging effect. However, tension at the incision after CD in large defects is related to an increased rate of pain and recurrence. We present the preliminary results of a new technique for medium midline hernias as an alternative to conventional CD. METHODS: A prospective controlled study was conducted from January 2015 to January 2017 to evaluate an elective new procedure (LIRA) performed on patients with midline ventral hernias (4-10 cm width). The posterior rectus aponeurosis was opened lengthwise around the hernia defect using a laparoscopic approach to create two flaps and was then sutured. The size of the flaps was estimated using a mathematical formula. An on-lay mesh was placed intraperitoneal overlapping the fascia defect. The data analyzed included patient demographics, operative parameters, and complications. A computerized tomography was performed preoperatively and postoperatively (1 month and 1 year) to evaluate recurrence, distance between rectus and seroma. RESULTS: Twelve patients were included. Mean width of the defect was 5.5 cm. Average VAS (24 h) was 3.9, 1.1 (1 month), and 0 (1 year). Mean preoperative distance between rectus was 5.5 cm; postoperative was 2.2 cm (1 year). Radiological seroma at first month was detected in 50%. Mean follow-up was 15 months. CONCLUSION: The LIRA technique could be considered as an alternative to conventional CD or endoscopic component separation for medium defects under 10 cm in width. This technique obtained a "no tension" effect that could be related to a lower rate of postoperative pain with no recurrence or bulging, being a safe, feasible, and reproducible technique.

Aproximación al análisis de las actitudes punitivas / An approach to the analysis of punitive attitudes / Abordagem à análise das atitudes punitivas

Resumen El objeto de estudio son las actitudes punitivas de la población. Se ha realizado una revisión de la literatura nacional e internacional sobre esta materia, a través de una búsqueda selectiva de estudios que han analizado las actitudes de la población hacia el castigo y el funcionamiento del sistema de justicia penal, como diseño metodológico. A partir del análisis documental se ha elaborado una síntesis de los rasgos más característicos de las actitudes punitivas y las diferentes metodologías utilizadas para su estudio. Los resultados ponen de relieve la complejidad de las actitudes y la necesidad de perfeccionar y combinar diferentes metodologías en el estudio de estas.

Abstract The object of study are the population's punitive attitudes. A review of the national and international literature on this subject has been carried out through a selective search of studies having analyzed the attitudes of the population towards punishment, and the functioning of the criminal justice system as a methodological design. From the documentary analysis, a synthesis of the most characteristic features of the punitive attitudes, as well as the different methodologies used for their study having been elaborated. The results contribute to highlighting the complexity of attitudes and the need to perfecting and combining different methodologies in their study.

Resumo O objeto do estudo é as atitudes punitivas da população. Uma revisão da literatura nacional e internacional foi feita nesta matéria, através de uma busca seletiva dos estudos que analisaram as atitudes da população para a punição, e a operação do sistema da justiça penal, como o projeto metodológico. Da análise documental, uma síntese das características mais próprias das atitudes punitivas e das metodologias diferentes usadas para seu estudo foi elaborada. Os resultados destacam a complexidade das atitudes e da necessidade para aperfeiçoar e combinar metodologias diferentes no estudo destas.

Correction to: Safety and effectiveness of self-adhesive mesh in laparoscopic ventral hernia repair using transabdominal preperitoneal route.

The metadata listed the wrong given names and family names.

La autoridad: verla en televisión y vivirla en familia / The authority: seeing it on television and living it in the family / Autoridade: vê-lo na televisão e viver em família

Este artículo de carácter analítico presenta resultados de una investigación hermenéutica cuyo objetivo fue comprender el sentido que le otorgan padres, madres, niños y niñas de distintos estratos socioeconómicos de Medellín y Envigado a las representaciones de autoridad agenciadas por la televisión. Los alcances de la investigación se orientan a desentrañar el papel cultural de la televisión en la configuración de las relaciones intergeneracionales. Se realizaron entrevistas y grupos focales y se halló que la televisión muestra un mundo infantil autonomizado definido por sus propias normas y relaciones igualitarias entre adultos y niños en contravía de las jerárquicas de la vida familiar. A pesar de su alto consumo, la televisión no es una mediación para la autoridad parental lo que replantea la postura tecnocéntrica adjudicada al medio.

This analytical paper shares results from a hermeneutical studythat aims to understand the meaning placed on representations of authority on television amongparents and their children. Participants in the study come from different social and economic levelsin the cities of Medellín and Envigado, Colombia. The research focuses on the cultural role oftelevision in shaping intergenerational relationships. Interviews and focal groups were conductedby the authors, identifying that television shows a childish autonomous world governed by its ownrules and equal relationships between adults and children, which go against the actual hierarchyof the family life. Despite the high number of hours that people watch, television is not shown to bean intermediary for parental authority, which disputes the technocentric position that is attributed tothis form of mass media

Este artigo de caráter analítico apresenta resultados de uma pesquisahermenêutica cujo objetivo foi compreender o sentido que lhe outorgam pais, mães, meninos e meninasde distintos estratos socioeconômicos de Medellín e Envigado às representações de autoridadeagenciadas pela televisão. Os alcances da pesquisa se focam a desentranhar o papel culturalda televisão na configuração das relações “intergeneracionais”. Na metodologia, se combinouentrevistas com grupos focais, a partir dos quais se demonstrou e se achou que a televisão mostra ummundo infantil autonomizado definido por suas próprias normas e relações igualitárias entre adultose crianças na contramão das relações hierárquicas da vida familiar. Embora seu alto consumo, atelevisão não é uma mediação para a autoridade parental o que reorienta a postura “tecnocêntrica”adjudicada ao meio de comunicação.

Safety and effectiveness of self-adhesive mesh in laparoscopic ventral hernia repair using transabdominal preperitoneal route.

BACKGROUND: Laparoscopic ventral or incisional hernia repair requires intraperitoneal mesh placement. This is associated with an increase in adhesions, bowel obstruction and enterocutaneous fistula. Intraabdominal meshes are laparoscopically fixed using traumatic fixation methods that increase acute, chronic pain and adhesions to bowel loops. The aim was to check the safety and effectiveness of the laparoscopic approach in ventral or incisional hernia, using a self-adhesive mesh in the preperitoneal space without tacks or transfascial sutures, and to objectively assess its benefits and complications. METHODS: Patients aged between 18 and 67 years old with medial, lateral ventral and incisional hernias between 3 and 8 cm in size were included in this study. Fifty patients were included in the study, which was conducted between January 2013 and March 2015. RESULTS: The average length of surgery was 57.3 ± 18 min. The average hospital stay was 1.1 ± 0.3 days. The average time taken to return to work was 9.2 ± 2.4 days. The most common post-operative complication was seroma, which was observed in 13 patients (26 %). The average follow-up was 15.4 ± 5.5 months. Three patients were lost to follow-up during this period. There was no hernia recurrence during examination nor on CT scan during the follow-up period. The average score on the visual analogue scale before surgery was 4 ± 1. After surgery, the score was as follows: 3 ± 0.8 on the first day after surgery, 0.9 ± 0.5 after the first week, 0.4 ± 0.4 after the first month and 0 after 90 days. No patient showed chronic pain. Overall satisfaction (VAS for surgery) was 8.3 ± 0.6. CONCLUSIONS: The use of self-adhesive meshes during the laparoscopic transabdominal preperitoneal approach in small- and medium-sized ventral or incisional hernias is safe and effective, with low post-operative pain, quick functional recovery and high overall satisfaction after surgery with no increase in recurrence in the short term.